From PKDCure.org, The PKD Foundation
I Have PKD
As someone living with and managing PKD, we know you have questions.
From PKDCure.org, The PKD Foundation
I'm a Health Professional or Researcher
The PKD Foundation is pleased to present a wide range of PKD-related information to help health professionals and researchers better understand PKD and help PKD patients.
Individuals and Families
From Foster's Daily Democrat, Dover
Kidney disease, need for transplants, growing problem
Despite his name being among more than 100,000 Americans waiting for a kidney transplant, Jonathan DuBois is making the most of his waiting time.
From PKDWillNotBeatMe.com, by Valen Keefer
In Honor of My Other Half
As I write this today, more than 10 years after receiving the gift of life, I am full of emotion and in awe at how my kidney transplant not only saved my life but it transformed that girl once depersonalized by her illness into the strong healthy woman I am today.
From theRecord.com, Kitchener, Canada
Kitchener man donates kidney to stranger to help ailing wife
Don Kraemer wanted to give his wife, Lori, the kidney she so desperately needed.
But his kidney wasn’t a match.
From Oldham Evening Chronicle, England
A KIND-HEARTED best pal is to carry out an extraordinary act - by donating a kidney to her friend’s husband.
From Lacey.Patch.com
Kidney Transplant a 'Second Birthday' for Lacey Woman
Amber Neumann, who was on New York's non-living donor list with a wait of five years, was part of a paired exchange April 4. Amber Neumann considers April 4 — the day she received a lifesaving kidney transplant — her "second birthday."
From the Tribune-Democrat, Ebensburg, PA
Mike and Lorie Bracken of Ebensburg have a special reason to celebrate during April’s National Donate Life Month.
From TransPlantCafe.com, a PKD discussion group
PKD Group
Symptoms
From PKDClinic.org
Polycystic kidney disease patients often find that their urine is foamy and if this condition lasts for long time or if it becomes worse, it indicates abnormal proteins pass through the glomerular filtration membrane.
From PKDClinic.org
Why PKD Patients Have High Creatinine In Blood
Sometimes PKD patients can find their serum creatinine level is higher than normal range and this means that their kidney functions are affected and at least more than 50% kidney functions are lost, therefore early and proper treatments should be sought to prevent further deterioration of kidney functions and slow down the illness progression into complete renal failure.
Treatment
How to Manage Leg Cramps in Polycystic Kidney Disease
Leg cramps happening in Polycystic Kidney Disease or other kidney diseases are thought to be caused by imbalances in fluid and electrolytes, but may also be caused by nerve damage or blood flow problems.
Can Polycystic Kidney Disease (PKD) Cause Osteoporosis
Kidneys perform important functions in our body. Remove waste products from the body. Balance the body’s fluids. Produce an active form of vitamin D that promotes strong, healthy bones. If the diseased kidneys can not function normally, the levels of calcium in body will reduce, thus resulting in osteoporosis
From PKDClinic.org
Can Polycystic Kidney Disease Patients Have Carrots
Polycystic kidney disease should have more fresh vegetables and fruits such as carrots, orange, date, kiwi fruit, etc. Fresh vegetables and fruits especially those that contain rich vitamins and iron such as carrot is good for PKD patients.
From PKDClinic.org
How to Treat Polycystic Kidney Disease Naturally
As polycystic cysts are filled with fluid, it is necessary to reduce the sac fluid if we want to shrink them. Some herbal medicines such as...
Information for Physicians
From SBWire, Naperville, IL
Polycystic Kidney Disease - Pipeline Review, H1 2013
Polycystic Kidney Disease - Pipeline Review, H1 2013', provides an overview of the indications therapeutic pipeline. This report provides information on the therapeutic development for Polycystic Kidney Disease, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Polycystic Kidney Disease.
Prognosis
From Kidney-Cares.org
Factors That Affect PKD Prognosis
It is known that PKD (polycystic kidney disease) will develop into renal failure. Usually it takes many years, however in some cases the illness can have rapid progression. About 50% PKD patients will enter into end stage renal disease when they are 57-73 years old
There are a variety of factors that can affect the prognosis and progression of PKD including genotype, gender, age, attack time, high blood pressure, hematuria (blood in urine), proteinuria (protein in urine), urinary tract infection, the size of the kidneys and renal cysts, pregnancy, steroids and other treatments. For example, if the patient has PKD 1 gene mutation, male, has the first onset of hematuria before 30 years old and develop high blood pressure before 35, he is very likely to develop renal failure early than others.
From PKDClinic.org
How Serious Is Polycystic Kidney Disease
Polycystic Kidney Disease is serious, because it can not be cured. What is worse, it progresses to kidney failure easily. It is a genetic kidney disorder, so people with parents suffering from Polycystic Kidney Disease have a high risk to experience this problem.
From PKDClinic.org
It is an illness that occurs in kidney, but in some cases, it may impair patients’ fertility.
Research
From Nature.com, an article preview
Metabolic reprogramming in polycystic kidney disease
A recent study shows that, like cancer cells, cells lacking the Pdk1 gene reprogram their metabolism to use aerobic glycolysis—the 'Warburg effect'. Targeting this pathway using a glucose analog that cannot be metabolized resulted in slower disease progression in mouse models of polycystic kidney disease. This work thus suggests a new potential therapeutic approach for autosomal dominant polycystic kidney disease
From Nature.com
From Financial Post, a news release
Phase III clinical trial results that form the basis of the regulatory filing were published online in the New England Journal of Medicine.
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